Abstract: The Xiaoqinling Au-Mo polymetallic ore-concentrated area with complex structure and active magmatism is characterized by continuous zones of Au-Mo-Ag geochemical anomalies and ideal metallogenic conditions.The small plutons in the area belongs to the high potassium calc-alkaline series, with relatively high acidity and moderately rich alkali, and there is a certain degree of crust-mantle mixing material involved in them.The large granite plutons are mainly emplaced on the intersection of EW-trending and NE-trending structures.While, subject to the strata-structure-magmatism united control, the small mineralized porphyries controlled by secondary structures are distributed around the large granite plutons or within small intrusives.The metallogenic model of tectono-magmatic activation is drawn from combination of geology, metallogenic regularity and mechanism etc.of Au-Mo deposits.Based on the regional mineralization regularity and prospecting practice, the systematic regional prospecting model is established, and ore prospects are outlined.