Abstract: This paper discusses the features and evolution of the tectonics in Guangxi and the possibility of the existence of the ancient continental crustal basement, and advances a new concept about the Youjiang and Qinzhou aulacogen type depressions. The author combines the tectonic movement with the material movement to study the features of the formation of uranium deposits and their temporal-spatial distribution in the region. Especially the tectonism at the geodepressional stage played a key role in the concentration of uranium and formation of uranium deposits.