Abstract: The Manzong gold lead silver polymetallic deposit occurs in the Sanmiancun magma arc in Tibet and is closely related to medium and fine grained hornblende biotite monzogranite of the Manzong unit and volcanic rocks of the Xieba Formation.The chemical and geochemical characteristics of the host rocks are favorable to mineralization.According to the characteristics of host rocks and thermosonimetric analysis of pyrite from orebodies with the BRC 1 type thermosonimeter,coupled with sulfur lead stable isotopic study,it is considered that this deposit is a mesothermal deposit associated with granitic magma.