Abstract: The Jinchanghe Fe-Cu-Pb-Zn polymetallic deposit in western Yunnan is located in the northern part of Baoshan block, and is one of the typical deposits in the Sanjiang polymetallic metallogenic belt.In this paper, the S-Pb isotope tracer study was carried out to explore the source of ore-forming materials, and the metallogenic mechanism of the deposit was summarized and studied in combination with the tectonic setting and metallogenic age. The results of sample testing show that the value of the δ³⁴S in the ore is +2.5‰~+11.1‰, and the average value is +5.65‰.The S isotope source is a variety of S isotope assemblages formed by deep mantle-derived magma and crust-derived material contaminated by magma.The Pb isotope compositions of ore minerals are ²⁰⁶Pb/²⁰⁴Pb 18.167~18.497, ²⁰⁷Pb/²⁰⁴Pb 15.668~15.779, and ²⁰⁸Pb/²⁰⁴Pb 38.554~38.997.The Pb isotopes are generally stable, indicating that the contamination of crust and mantle was dominated by lead in the upper crust, possibly from deep intrusive magma and ore-bearing Cambrian strata.The deposit characteristics of composite mineral sources show an inferred multi-source, deep source shallow source, and the mineralization of the acidic rock should be buried in the depth.