Abstract: Exemplified by the national poverty alleviation crucial area of Qixingguan District in Wumengshan of Guizhou Province, referring to the evaluation theory and method for "national geological resources and environment carrying capacity evaluation and monitoring and early warning", and combined with the hydrogeologcal conditions of groundwater resources of the karst mountain area and the practical development and utiization situation, the authors explored the construction of water resources carrying capacity evaluation method for counties in the karst mountain area. The carrying capacity of groundwater resources in Qixingguan area was systematically evaluated, and it is concluded that the carry capacity of groundwater resources in this area is relatively large, but the uneven distribution of inferior water and resource exploitation intensity reduce the carrying capacity of groundwater resources in some places. The evaluation results provide the basis for regional land space planning and "three districts and three lines" designation.At the same time, the evaluation method also provides reference for the evaluation of carrying capacity of groundwater resources in karst areas.