Abstract: The Bangzhuoma gold deposit is one of the most potential deposit for prospecting in Gangdise-Himalaya Au-Sb polymetallic metallogenic belt of southern Tibet. The analysis and study of the genesis and metallogenic model of the Bangzhuoma gold deposit have important guiding and reference significance for defining the mineralization type and carrying out the further oreprospecting work. After collecting the geological data of the Bangzhuoma gold deposit, such as ore-forming tectonic background, regional strata, geological structure and igneous rocks, the authors analyzed geochemical characteristics and ore-bearing potential of the host strata and igneous rocks in this area. The results show that the Upper Triassic strata seem to have been its host rocks which might have provided initial ore source, and the medium-basic intrusive rocks of Early Cretaceous and the acid intrusive rocks of Neogene provided thermal energy, kinetic energy and some ore-forming materials. In addition, the ore-controlling factors and ore deposit genesis of the deposit were analyzed systemically in the aspects of strata, magmatic rocks, structure and H-O-S-Pb isotopes. Five orebodies were delineated preliminarily, and the sources of ore-forming materials and fluids were revealed. Based on the results obtained, the authors hold that the Bangzhuoma gold deposit bears low temperature shallow-seated hydrothermal features. The metallogenic model and prospecting pattern of this ore deposit were established on the basis of the above-mentioned study.