Abstract: This paper systematically summarizes the characteristics of mineralization types and resource potential of gold, copper, tin and iron deposits. The copper deposits are from small to medium in size in Bolivia, and the main mineralization types are red-bed copper, sediment-associated vein-type deposits, VMS, IOCG and some other types. The gold deposits are from small to medium in size, and the main deposit types are the volcanogenic epithermal deposits (vein-type or porphyry), vein-type deposits associated with felsic plutons, orogenic gold (±antimony) deposits and placer gold deposits. Bolivia has many large and superlarge tin deposits, and the typical mineralization types are "Bolivia-type" polymetallic veins and pluton-associated polymetallic vein deposits, with minor placer tin deposits. The superlarge Mutún iron-manganese deposit is hosted in Banded Iron Formation (BIF). Western Cordillera and Altiplano have important potentiality for discovering epithermal precious metal resources. North Eastern Cordillera mainly contains potential of tungsten, tin, gold, antimony resources, and central Eastern Cordillera has potential of tin, silver and gold, antimony resources, with gold, antimony, silver, lead and zinc in the south segment. Important silver-zinc resources occur in south Subandean. Chaco-Beni plain has extensive placer gold resources. Precambrian craton contains potential of gold, platinum, nickel, tantalum, copper, iron and manganese resources.