Abstract: Located in the Chetwynd area along southwest coast of the Newfoundland island, the Hope Brook gold deposit is the sixth largest gold deposit in Canada. The Hope Brook gold deposit occurs in Avalon Zone intrusive body of Neoproterozoic Appalachian Mountain. Its has an area of 3000×400m2 at surface but is gradually reduced with the depth. The deposit has complex veined structure, and is closely associated with felsic and mafic pyroclastic rocks of the pyroclastic sequence. The deposit occurs in a large hydrothermal alteration area charecterized by argillic alteration. Isotope chronological evidence shows that the metallogenic epoch is Early Cambrian- Middle Cambrian (576±10Ma). The deposit experienced several times of hydrothermal activities, accompanied by joint effect of magmatic intrusion and tuff produced by volcanism, and hence should belong to a typical high sulfidation epithermal gold deposit.