Abstract: In recent years, the proved reserves for the Gejiu superlarge tin-polymetallic ore concentration area have been consumed excessively and the situation of mining industry has become extremely critical. Therefore, the exploration of the deep space has become the prospecting focus in this area. Based on analyzing geological backgrounds and prospecting model systematically in the Zhulin ore block and employing the concept of 3D geological modeling, the authors built the 3D geological model of surface, strata, rocks, structures and orebodies with Surpac software in the study area according to geological sections along the exploration lines, engineering deployment maps and topographic and geological maps. In addition, the authors chose and utilized the weight of evidence method to predict and evaluate mineral resources at great depth and, as a result, delineated four targets through optimization. The prognostic depth reached 2550m. The prediction results show that 61.02% of the known ore body is consistent with the prognostic prospective area in space, which indicates that the prediction is accurate and the prediction method based on 3D visualization technology is effective.