Abstract: Potential resources forecast and assessment of 25 kinds of metals in the Project of National Mineral Resources Assessment have been accomplished. Based on systematic collection of forecast achievements and materials of 23 kinds of metal resources excluding uranium and coal, the authors analyzed resources potential of these 23 kinds of metal resources with the regional value estimating method. The results show that iron has the biggest economic value in China, followed by REE and then copper and gold. The iron concentration area in An-Ben area of Liaoning Province, REE concentration areas in Bayan Obo, southern Three Rivers Region, Southwest China, Gangdise area and Tibet have tremendous economic value with considerable mineral resources potential. These areas can be called mineral economic centers in China and should also be regarded as the most important mineral exploration areas that should enjoy the priority in exploration deployment. 100 polymetallic key geological exploration areas were delineated through sieving, where big exploration breakthrough is likely to occur in the nearest future, and resource replacement bases will be formed through better cultivation and optimization. The results achieved by the authors are of great significance for realizing national mineral resource defense strategy and accomplishing the objective of National “358” Exploration.