Abstract: Taking Xieliupo landslide developed in Pingding-Huama fault zone as an example, this paper deals in detail with the deformation characteristics and formation mechanism, and proposes the prevention and control method and treatment measures on the basis of field investigation and analysis of deformation monitoring data of fault zone landslides. A fault zone landslide is generally a large or giant landslide, which consists of quite a few secondary landslides. The landslide took place time after time historically. According to the measurement data obtained in recent years, Xieliupo landslide deformation occurs as creeping - tensile fracture (plastic flow tensile fracture) - soil (or rock) debris flow, which is at the stage of constant speed creep deformation at present. The long-term activity of Pingding-Huama fault and fracture zone has provided material basis of landslides activity for prolonged creep-slip; however, rainfall is the main factor that triggers these landslides, resulting in the loss of stability. Therefore, the control of the fault zone landslide should be focused on prevention, supplemented by treatment. That is, the landslide control should be based on real-time monitoring and mass prediction, supplemented by disaster prevention composed of landslide surface dewatering and slope toe loading. The control could slow down or prevent the landslide from inducing disaster again.