Abstract: Although the conventional geochemical methods are thought better effect methods which are used to prospect and explore in the all kinds of coverage area, it is not clear what their most effective role is in prospecting in the Karst residual slope laminated coverage area Pinggui area in Guangxi province. This research is mainly concerned with a study of anomaly characteristics of soil ionic conductivity on tin deposits in Pinggui area in Guangxi Province. The investigation to test the validity of prospecting in the approach was carried out above the known ore bodies revealed that the clear soil ionic conductivity anomalies are detected over ore bodies，and which appeared two typical summits resembling shapes which are look like a "rabbit ear" or "hard iron teeth". Further research needs to be conducted to determine by experiment that the main water soluble ions which make up the anomaly of soil ionic conductivity of tin deposits are including SO42-, Ca2+, HCO3-, Cl-, Fe3+, Mg2+, Na+, K+, Mn2+ and F- , and their relation degree between the tin anomaly are as follow: SO42-＞Ca2+＞HCO3-＞Cl-＞Fe3+＞Mg2+＞Na+＞K+＞Mn2+＞F-.This fruitful work provided theory basis to explain soil ionic conductivity anomaly. On the basis of it , we finally carried out prospecting prediction by this method in the area and found two predictive targets where five ore bodies were found by the engineering drill.