Abstract: Making use of the existing commercial three-dimensional geological modeling software to establish three-dimensional spatial model of regional geology, construction, drilling and ore body under the guidance of metallogenic prediction. Estimating and interpolating the ore body grades on this basis, we establish cube prediction model of research district and analyze the uneven distribution of ore bodies from the three-dimensional view. Applying algorithm of three-dimensional contour extraction and ore grade description to analyze the 3D morphology and grade distribution of ore body detailed on the basis of cube prediction model and guiding us to a new direction of mining exploration in the future.