Abstract: The metallogenetic belt in the Middle-South Peninsula of Southeastern Asia where is rich in mineral resources is an important component of the Tethyan (Mediterranean – Himalayan - Southeastern Asia) intercontinental metallogenetic domain. This metallogenetic belt, bounded by the suture zones and deep seated faults, is initially divided into five metallogenetic provinces and nineteen metallogenetic zones respectively based on the compiling map of geological and mineral resources combined with the other′s research in this region. The following conclusions are drawn in this paper: (a) the metamorphic Fe-Cu-REE deposits were formed in the Proterozoic crystal bases; (b) the Cr-Fe deposits and Cu-Ni sulfide deposits associated basic and ultra-basic intrusions in the suture zones; (c) the salt deposits in the structure depressions intra-plates; (d) porphyry Cu-Au deposits, hydrothermal Pb-Zn deposits, hydrothermal vein Au deposits, and hydrothermal vein W-Sn deposits were formed in different stages during orogenic evdution, and associated with different types of granites. This research provides not only a basic frame for wholly understanding ore-forming regularity of this region, also new enlightenments for searching for the mineral deposits similar to ones discovered in adjacent countries.