Abstract: Interpolation is playing an important role in evaluation of mineral reserves, and is also an overwhelming computation that makes it needed to find a tradeoff between the density of interpolating and the time of calculating. The research is taken to move the interpolation from CPU to graphic card by means of CUDA, and has improved much the speed of the calculation. An experiment on evaluation the Zijinshan copper mine data showed the merit, and a result of acceleration of 67 times was achieved by compared the calculations of CPU based and GPU based.