Abstract: This paper deals with the geological, petrological, geochemical and isotope geochemical characteristics of Variscan granite porphyry （Moshiling unit） and Indosinian granite （Heshangtang unit）. Material and data indicate that the former is intraplate granite, while the latter syncollision granite. The ages of the two types of granite just coincide with the closing fo the Paleo Tethys of western Yunnan and opening of the Mid Tethys.