Abstract: The study area Liukuaidi South is located in the central and eastern part of Heilongjiang Province.The tectonic position belongs to the Xiaoxinganling-Zhangguangcailing magmatic arc.The metallogenic zone is an important part of the Yichun-Yanshou polymetallic metallogenic subbelt, and the metallogenic geological conditions are superior.To find out the distribution characteristics of ore-forming elements and ore-forming bodies in the study area and achieve the ore-prospecting breakthrough, a 1:20000 soil geochemical survey and ore-forming prediction were carried out.The correlation analysis, cluster analysis, factor analysis, single element anomaly analysis, and combined element anomaly analysis of 12 metallogenic elements are used to delineate the element anomaly area and optimize the prospecting target area.The results show that the variation coefficients of Au, As, Sb, and Mo are high and the metallogenic potential is strong.The correlation coefficient of As and Sb elements was 0.73.The metallogenic elements were divided into four groups by R-type cluster analysis and four groups by factor analysis.Combined with the ore-forming geological conditions and soil geochemical anomaly characteristics, 113 single-element anomalies and 3 combined anomalies were identified.The main ore types in the test area are Au and Zn, the main Au prospecting target areas are Au-5 and Au-7 abnormal areas, and the main Zn prospecting target areas are Zn-6 abnormal areas.Sb and Mo have very good prospecting prospects and can be used as the first prospecting target elements.