Abstract: The Northeast Africa mainly includes Egypt, Sudan, Eritrea and Ethiopia, hosting rich mineral resources such as gold, silver, copper and zinc, and the main types of mineral deposits are VMS.Since the discovery of large VMS deposits such as Ariab and Bisha, mining companies from various countries have been conducting exploration and mining in this region, and the discovery of a large number of new deposits elevate the mineral resources of copper and gold.The summary of exploration and research progress of VMS deposits in those countries can provide references for enterprises that carry out mineral exploration and investment in this region.The host rocks of VMS deposits in this region are mainly bimodal felsic volcanic rocks, which indicate a certain correlation with the volcanic arc rock combination, and the main controlling factors for the deposits are shear zones, folds and characteristic metamorphosed volcanic-sedimentary series.The ages of these deposits are mainly concentrated in three stages ranging from 890 Ma to 695 Ma, and were formed in two types of paleotectonic environments, island arc on the margins of convergent plates and back-arc basin in the oceans.Most deposits experienced near-surface oxidation and supergene enrichment, with gold and copper relatively enriched near surface.The discovered VMS deposits are mainly distributed in the north-central part of the Arabian Nubian Shield, including Barka, Gabgaba, Eastern Desert terranes, and the prospects are near the Barka, Nakasib, Keraf, and Nugrus suture zones.