Abstract: The research on the relationship between deep lithospheric process and mineralization is the forefront of Geoscience. It is of great significance to deepen understanding of metallogenic geological setting, summarize metallogenic regurality, effectively assess resource potential and improve the effect of mineral exploration.Based on the new tectonic units of the African Continent divided by lithosphere, the temporal-spatial distribution of mineral resources was analyzed, and the metallogenic characteristics in different types of lithosphere such as craton, orogeny and rift were analyzed.According to the formation and lithospheric evolution of the African Continent, the crust-mantle status of different types of lithosphere in the African Continent was distinguished, that is, the age of material formation and the age of structure formation.Combined with the spatial distribution of main mineral resources, genetic types of ore deposits and assemblage of mineral resources, 27 metallogenic belts in the present African Continent were divided.It is a useful exploration and attempt to examine and divide the metallogenic belt of the African Continent from the "dynamic" view of geological process, which is based on the relationship between deep geological process and mineralization.It would provide a new idea and reference for mineral resource evaluation and prospects generation in Africa.