Abstract: Objective Conventional prospecting methods have poor effectiveness in evaluating the exploration of pegmatite type lithium deposits in coverage areas, and it is particularly important to find an effective combination of prospecting techniques and methods. The discovery of the Saka lithium mine in Nasarawa is a successful case of using comprehensive prospecting methods to search for pegmatite type lithium deposits in thick covered areas of Nigeria. Methods The study used the "rock transformation mapping method" to discover clues of pegmatite veins in mining areas, supplemented by soil geochemical profile measurement, induced polarization gradient measurement, audio magnetotelluric sounding and other methods to further determine the morphology and scale of pegmatite veins, providing a basis for effective verification of drilling engineering. Results Through comprehensive study of multi-source information such as geological characteristics, geochemistry, and geophysical anomalies in the mining area, the prospecting indicators of the mining area were summarized, and geomorphic prospecting indicators such as regular terrain and mountain ranges were proposed; Lithium mineralization is related to electrical and petrochemical processes, as well as sodium feldspar mineralization. The stronger the sodium feldspar mineralization, the stronger the lithium mineralization process; Areas with high apparent resistivity anomalies, large scale and distinct gradients of Li, Be, Nb, Rb and other elements can serve as important indicators for searching for pegmatites. A comprehensive geological geochemical geophysical exploration model for the mining area has been established, and drilling has verified the discovery of thick and large lithium ore bodies in deep areas. Conclusions The successful application of comprehensive prospecting methods has certain indicative significance for the direction of regional prospecting, and has important reference and promotion significance for the future search for pegmatite lithium deposits in Nigeria.