Abstract: Under the influence of global warming and a humidifying climate, the frequency of the rock-ice avalanche disaster is steadily increasing. Among these, the occurrence of ice-rock avalanches is primarily controlled by ice-rock mixtures at the contact zones between glaciers and bedrock. However, the deterioration mechanisms of ice-rock mixtures and the formation processes of the ice-rock avalanche-debris flow disaster chain remain unclear. This study focuses on the Chaqu Basin of the Qinghai-Tibet Plateau. Temperature-controlled triaxial experiments were conducted to investigate the failure characteristics of ice-rock mixtures under conditions of -8°C~0°C, ice-rock ratios of 0.25~0.75, and confining pressures of 200~400 kPa. Additionally, the motion patterns of the Chaqu BC01 high-altitude ice-rock avalanche hazard under -4°C conditions were analyzed using Massflow simulations. The results indicate that the peak shear strength, internal friction angle, and cohesion of ice-rock mixtures decrease with increasing temperature. As temperature rises, the strength variation of ice-rock mixtures transitions from strain softening and shear failure to strain hardening and dilatancy failure. With an increasing ice-rock ratio, the stress-strain characteristics of the mixtures shift from strain softening to strain hardening. Using the Mohr-Coulomb strength criterion and Boltzmann function, the relationships among strength, ice-rock ratio, and temperature were characterized, and a strength failure criterion incorporating temperature and ice-rock ratio parameters was established. Under extreme weather conditions, the Chaqu ice-rock avalanche is prone to forming an ice-rock avalanche-debris flow-river blockage disaster chain, which could obstruct the Palongzangbu River, posing significant threats to residents and infrastructure in the Palongzangbu River Basin.