Abstract: Duwen highway in Sichuan province is located in the strong earthquake zone of the 2008 Wenchuan earthquake, where post-earthquake debris flow disasters are exceptionally active. The debris flow disasters causes serious damage to human property and poses a major threat to human security. In order to find out the spatial distribution pattern of the material sources on the mountain slopes and explore the causes of the mudslide material sources in the earthquake area, pre-earthquake DEM, post-earthquake Landsat TM multi-band fusion data, and two-phase full-color band remote sensing data of typical debris flow gullies in the area were selected to analyze the characteristics and evolution of debris flow source development. The results show that the development of debris flow sources is significantly controlled by the combined effects of terrain slope direction, slope gradient, elevation, and water system in the strong earthquake zone of the Wenchuan earthquake. There is a "back slope amplification effect" and "reverse (displacement) direction amplification effect" on the slope direction, and the elevation and slope gradient are related to the dynamic process of mountain slope development. The release of seismic energy is the basis for the development of debris flow sources. An index relationship model between the density of debris flow source development in the strong earthquake zone and seismic intensity was established, and it was believed that the presence of faults in the study area may promote further development of debris flow sources. The evolution of debris sources is characterized by area reduction and disappearance, the disintegration of large sources into multiple small sources, the convergence of small sources leading to an increase in scale, source migration, and the emergence of new sources.