Abstract: The Yindongpo gold deposit is a super large gold deposit located in Zhuzhuang Town, Tongbai County, Henan Province, associated with silver, lead and zinc. This paper applies the prospecting prediction methods and theories in the exploration area to construct a "trinity" geological model for prospecting prediction, which focuses on the ore-forming geological body, ore-forming structure, ore-forming structural plane, and the characteristic markers of mineralization. Based on field investigation and mineral deposit study, the Yindongpo deposit has been suggested as middle-low temperature (200~350℃) magmatic-hydrothermal deposit, related to magmatic activities at Early Cretaceous. C-H-O-S isotopes indicate that ore-forming materials and fluids mainly originated from magmas. The metallogenic geological body is determined as concealed Early Cretaceous pluton in deep part of the Yindongpo deposit. Metallogenic structural plane is lithologic interface (silicon/calcium interface), structural plane of fold metallogenic tectonic system, structural plane of sedimentary diagenesis. Mineralization indicators are skarn, potassic alteration, beresitization, silicification, iron dolomitization, fluorite, and carbonation. Ore prediction model has been established, defining prospecting area, and 85% drill hole witnessed mineralization, achieving exploration breakthrough. The work has been meaningful in guiding to next ore exploration step.